SCHEMBL23400151

SCHEMBL23400151

Cc1ccccc1-n1cc(O)c(C(C)C)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.40
ADORA2A P29274 2/20 0.40
HSP90AA1 P07900 2/20 0.39
HSP90AB1 P08238 1/20 0.39
FLT3 P36888 1/20 0.38
GSK3B P49841 1/20 0.38
ATP4A P20648 1/20 0.36
ATP4B P51164 1/20 0.36
TYMS P04818 1/20 0.36
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
DHODH Q02127 1/20 0.33
CTSA P10619 1/20 0.33
RXRA P19793 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400912 0.80 ADORA3 (0.43) ADORA3ADORA2AHSP90AA1FLT3GSK3B
SCHEMBL23398439 0.78 NPC1 (0.47) ALDH1A1SMN1; SMN2MEN1PKMKMT2A
SCHEMBL23401239 0.77 HSP90AA1 (0.42) ADORA3ADORA2AHSP90AA1HSP90AB1FLT3
SCHEMBL23400099 0.77 KDM4E (0.41) ADORA3ADORA2AHSP90AA1HSP90AB1FLT3
SCHEMBL23399059 0.75 ADORA3 (0.45) ADORA3ADORA2AFLT3GSK3BATP4A
SCHEMBL23403188 0.74 ADORA3 (0.43) ADORA3ADORA2AFLT3GSK3BALDH1A1
SCHEMBL23403407 0.74 ADORA3 (0.40) ADORA3ADORA2AFLT3GSK3BATP4A
SCHEMBL23401227 0.74 ADORA3 (0.40) ADORA3ADORA2AHSP90AA1HSP90AB1FLT3
SCHEMBL23402790 0.74 ADORA3 (0.40) ADORA3ADORA2AHSP90AA1FLT3GSK3B
SCHEMBL23398718 0.73 NPC1 (0.49) ADORA3ADORA2AHSP90AA1HSP90AB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed