SCHEMBL23400289

SCHEMBL23400289

Nc1c(-c2ccccc2)n(-c2ccccc2)n(C2CCCC2)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
BCHE P06276 1/20 0.38
PTGS2 P35354 1/20 0.38
ALOX15 P16050 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 1/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
OGFRL1 Q5TC84 1/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401379 0.99 ALDH1A1 (0.41) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23401070 0.81 BCHE (0.53) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23402467 0.80 BCHE (0.51) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23402157 0.79 BCHE (0.40) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23399419 0.78 PDE4A (0.40) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23400271 0.78 BCHE (0.39) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23401864 0.78 ALDH1A1 (0.36) ALDH1A1ALOX15NPSR1GAADRD2
SCHEMBL23401272 0.77 CNR1 (0.40) ALDH1A1BCHEPTGS2ALOX15NPSR1
SCHEMBL23402967 0.76 BCHE (0.51) ALDH1A1BCHEPTGS2ALOX15TSHR
SCHEMBL23398632 0.75 BCHE (0.56) ALDH1A1BCHEPTGS2ALOX15NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed