SCHEMBL23401016

SCHEMBL23401016

Cc1ccc(-n2nc(CC(C)C)c(C(C)C)c2O)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 2/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPC1 O15118 3/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
RAB9A P51151 2/20 0.36
PAX8 Q06710 1/20 0.36
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 1/20 0.34
STAT1 P42224 1/20 0.34
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402069 0.88 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23400025 0.86 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23399134 0.85 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23401747 0.85 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23401855 0.85 KDM4E (0.37) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23399154 0.83 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23399286 0.83 ALDH1A1 (0.40) ALDH1A1TP53NPC1LMNARAB9A
SCHEMBL23399259 0.83 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATP53CYP1A2
SCHEMBL23398416 0.82 CA1 (0.44) ALDH1A1TP53SMN1; SMN2KDM4EHPGD
SCHEMBL23400327 0.81 CYP1A2 (0.47) ALDH1A1MEN1KMT2ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed