SCHEMBL23401262

SCHEMBL23401262

CCCc1nn(C)c(-c2cccc(C)c2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
TP53 P04637 3/20 0.45
MAPT P10636 2/20 0.45
THRB P10828 1/20 0.45
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
TDP2 O95551 1/20 0.37
TGFBR1 P36897 1/20 0.37
TLR8 Q9NR97 1/20 0.37
RIPK2 O43353 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PDE5A O76074 1/20 0.36
NMT1 P30419 1/20 0.35
KMO O15229 1/20 0.35
HEXA P06865 1/20 0.35
HEXB P07686 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399250 0.92 TP53 (0.47) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23401944 0.89 HEXA (0.43) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23401087 0.88 TP53 (0.44) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23398968 0.86 NPC1 (0.44) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23400396 0.85 TP53 (0.46) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23399820 0.84 PDE5A (0.45) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL23399167 0.83 RIPK2 (0.44) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23403043 0.83 TP53 (0.41) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23400037 0.83 ALDH1A1 (0.45) RAB9ANPC1TP53MAPTTHRB
SCHEMBL23402943 0.82 MAPT (0.40) RAB9ANPC1TP53MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed