SCHEMBL23401263

SCHEMBL23401263

Cc1cnn(C(C)(C)C)c1O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
CYP17A1 P05093 1/20 0.35
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
TSHR P16473 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP2D6 P10635 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27497190 0.80
SCHEMBL12960396 0.76 CYP1A2 (0.37) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL23398615 0.76 ALDH1A1 (0.36) CYP1A2CYP2C9TSHRALDH1A1SMN1; SMN2
SCHEMBL23402958 0.74 CYP1A2 (0.38) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL21720617 0.73 CYP1A2 (0.35) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL21718834 0.73 CYP1A2 (0.35) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL24275822 0.73 CYP1A2 (0.35) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL17045700 0.73 TSHR (0.39) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL21718648 0.73 CYP1A2 (0.35) CYP1A2CYP17A1CYP3A4CYP2C9TSHR
SCHEMBL23399663 0.73 CYP17A1 (0.32) CYP1A2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed