SCHEMBL23401282

SCHEMBL23401282

Cc1ccc(-c2nn(C(C)C)c(C(C)(C)C)c2O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ABL1 P00519 8/20 0.37
EGFR P00533 8/20 0.37
SRC P12931 8/20 0.37
KDR P35968 8/20 0.37
MTOR P42345 8/20 0.37
PIK3CD O00329 7/20 0.37
HCK P08631 7/20 0.37
PIK3CA P42336 7/20 0.37
PIK3CB P42338 7/20 0.37
PIK3CG P48736 7/20 0.37
EPHB4 P54760 7/20 0.37
PRKDC P78527 7/20 0.37
PI4KB Q9UBF8 7/20 0.37
RET P07949 2/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
HPGD P15428 2/20 0.33
RPS6KA3 P51812 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399033 0.86 ESR1 (0.42) ESR1ABL1EGFRSRCKDR
SCHEMBL23399831 0.81 PIK3CD (0.40) ESR1ABL1EGFRSRCKDR
SCHEMBL23402234 0.80 ESR1 (0.42) ESR1ABL1EGFRSRCKDR
SCHEMBL23399817 0.80 SMN1; SMN2 (0.37) ABL1EGFRSRCKDRMTOR
SCHEMBL23401165 0.80 HTR2A (0.47) ESR1ABL1EGFRSRCKDR
SCHEMBL23398454 0.79 HTR2A (0.35) ESR1RETHTR2AHTR2CHTR2B
SCHEMBL23399350 0.78 KDM4E (0.36) HPGDKDM4EALDH1A1FYNMEN1
SCHEMBL23398932 0.78 RIPK2 (0.46) ABL1EGFRSRCKDRMTOR
SCHEMBL23401036 0.78 EGFR (0.39) ESR1ABL1EGFRSRCKDR
SCHEMBL31617528 0.76 TMEM97 (0.43) ESR1ABL1EGFRSRCKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed