SCHEMBL23398454

SCHEMBL23398454

Cc1ccc(-c2c(O)nn(C(C)C)c2C(C)(C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
RET P07949 1/20 0.32
FPR1 P21462 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ESR1 P03372 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398499 0.81 HTR2A (0.38) HTR2AHTR2CHTR2BRETALDH1A1
SCHEMBL23402939 0.80 ALDH1A1 (0.33) ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL23400953 0.80 HTR2A (0.47) HTR2AHTR2CHTR2BRETALDH1A1
SCHEMBL23401282 0.79 ESR1 (0.39) HTR2AHTR2CHTR2BTMEM97SIGMAR1
SCHEMBL23403048 0.78 MEN1 (0.33) ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL23401950 0.78 HPGD (0.37) RETALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL23400454 0.78 HTR2B (0.37) HTR2AHTR2CHTR2BRETALDH1A1
SCHEMBL23399107 0.77 SMN1; SMN2 (0.40) ALDH1A1MEN1KMT2ASMN1; SMN2TSHR
SCHEMBL23403636 0.76 PTGS2 (0.34) TMEM97SIGMAR1ALDH1A1MEN1KMT2A
SCHEMBL23400772 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed