SCHEMBL23401359

SCHEMBL23401359

CCCc1c(O)c(CC(C)C)nn1-c1ccc(OC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 2/20 0.40
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
HSD11B1 P28845 1/20 0.35
PTGS1 P23219 2/20 0.35
PTGS2 P35354 2/20 0.35
NPBWR1 P48145 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403176 0.93 KMT2A (0.37) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23400256 0.90 PDE4D (0.42) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23398465 0.90 PDE4D (0.39) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23401776 0.90 LMNA (0.38) PDE4DALDH1A1LMNAPOLBPTGS1
SCHEMBL23399966 0.88 PDE4D (0.46) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23402472 0.87 PDE4D (0.42) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23400453 0.86 CACNA1H (0.36) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23399978 0.85 PDE4D (0.41) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23403046 0.85 PDE4D (0.39) PDE4DPDE4APDE4BPDE4CALDH1A1
SCHEMBL23403479 0.84 CACNA1H (0.44) ALDH1A1MAPTCYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed