SCHEMBL23401412

SCHEMBL23401412

CCCCc1nn(-c2ccc(C)cc2)c(-c2ccccc2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
ADORA3 P0DMS8 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
LMNA P02545 2/20 0.40
MAPK1 P28482 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
ESR1 P03372 1/20 0.40
TP53 P04637 1/20 0.40
CYP2D6 P10635 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398384 0.95 MAPT (0.46) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23401729 0.93 MAPT (0.46) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23399744 0.92 CYP2C9 (0.45) MAPTCYP2C9CYP2C19CYP1A2CYP3A4
SCHEMBL23401465 0.92 CNR1 (0.47) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23401496 0.89 L3MBTL1 (0.44) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23402407 0.87 MAPT (0.45) MAPTCYP2C9CYP2C19ADORA3CYP1A2
SCHEMBL23402169 0.87 CYP2C9 (0.43) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23398515 0.86 RPA1 (0.44) PDE4APDE4BPDE4CPDE4DCYP2C9
SCHEMBL23403159 0.86 RPA1 (0.44) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL23401408 0.85 MAPT (0.51) MAPTPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed