SCHEMBL23401417

SCHEMBL23401417

CCc1nn(CC)c(-c2ccccc2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ADORA2A P29274 1/20 0.45
KDM4E B2RXH2 4/20 0.42
MAPK1 P28482 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
TNNI3 P19429 1/20 0.42
CRHBP P24387 1/20 0.42
CASP1 P29466 1/20 0.42
TNNT2 P45379 1/20 0.42
CASP7 P55210 1/20 0.42
TNNC1 P63316 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
CRHR2 Q13324 1/20 0.42
KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400102 0.87 MAPT (0.44) ADORA2AKDM4EMAPK1MEN1CRHBP
SCHEMBL23398785 0.87 HTR2A (0.48) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23399225 0.85 MAPT (0.41) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23402284 0.84 HTR2A (0.43) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23400675 0.84 CNR2 (0.39) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23399345 0.84 HTR2A (0.43) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23402096 0.84 NR1H3 (0.49) MEN1CRHBPKMT2ACRHR2MAPT
SCHEMBL23403577 0.83 NPC1 (0.45) HTR2CADORA2AKDM4EL3MBTL1MAPT
SCHEMBL23402612 0.83 GRM5 (0.42) CA1CA2KDM4EMAPK1MEN1
SCHEMBL28893567 0.81 SMN1; SMN2 (0.37) HTR2AHTR2CHTR2BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed