SCHEMBL23398785

SCHEMBL23398785

CCCc1nn(CC)c(-c2ccccc2)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
HTR2B P41595 1/20 0.48
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
KDM4E B2RXH2 4/20 0.40
MAPK1 P28482 3/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
USP2 O75604 2/20 0.40
CRHBP P24387 2/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
CRHR2 Q13324 2/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40
ATM Q13315 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399345 0.91 HTR2A (0.43) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23402189 0.89 MAPT (0.43) HTR2AHTR2CHTR2BKDM4EMAPK1
SCHEMBL23401417 0.87 HTR2A (0.47) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23398901 0.86 NR1H3 (0.48) KMT2AMEN1CRHBPCRHR2MAPT
SCHEMBL23400492 0.86 MAPT (0.39) HTR2AHTR2CHTR2BKDM4EMAPK1
SCHEMBL23402422 0.85 ALDH1A1 (0.38) HTR2AHTR2CHTR2BKDM4EL3MBTL1
SCHEMBL23399820 0.84 PDE5A (0.45) CA1CA2KDM4EMAPK1KMT2A
SCHEMBL23398968 0.84 NPC1 (0.44) HTR2AHTR2CHTR2BKDM4EL3MBTL1
SCHEMBL23401536 0.82 USP2 (0.36) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL23399575 0.81 CYP2C9 (0.46) HTR2AHTR2CHTR2BKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed