SCHEMBL23401640

SCHEMBL23401640

Cc1ccccc1-c1[nH]n(-c2ccccc2C)c(=O)c1CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
NOX4 Q9NPH5 1/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.33
MGLL Q99685 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ATM Q13315 1/20 0.33
CASP3 P42574 1/20 0.33
CASP6 P55212 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399458 0.87 NOX4 (0.43) MAPTLMNANOX4KMT2AMEN1
SCHEMBL23402078 0.87 MAPT (0.46) MAPTHTTLMNAKMT2AMEN1
SCHEMBL23401023 0.85 KDM4E (0.42) MAPTHTTLMNANOX4KMT2A
SCHEMBL23399825 0.85 MAPT (0.48) MAPTHTTLMNAKMT2AMEN1
SCHEMBL23398782 0.85 NOX4 (0.39) MAPTHTTLMNANOX4KMT2A
SCHEMBL23400793 0.83 GAA (0.43) MAPTNOX4ALDH1A1SMN1; SMN2MGLL
SCHEMBL23402597 0.83 NOX4 (0.46) MAPTHTTLMNANOX4KMT2A
SCHEMBL23401013 0.82 BRD4 (0.38) MAPTHTTKMT2AMEN1ALDH1A1
SCHEMBL23402776 0.82 NOX4 (0.37) MAPTHTTLMNANOX4KMT2A
SCHEMBL23401270 0.81 MAPT (0.35) MAPTHTTLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed