Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401777 | 0.93 | NPC1 (0.59) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL23400195 | 0.91 | NPC1 (0.58) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL23402767 | 0.91 | NPC1 (0.58) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL15345094 | 0.85 | NPC1 (0.74) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL23403116 | 0.85 | KMT2A (0.51) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL23399371 | 0.84 | NPC1 (0.62) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL23401411 | 0.83 | NPC1 (0.68) | NPC1RAB9AKMT2AMAPTTP53 | |
| SCHEMBL23401483 | 0.83 | NPC1 (0.59) | NPC1RAB9AKMT2AMAPTTP53 | |
| SCHEMBL23403231 | 0.83 | KMT2A (0.52) | NPC1RAB9AKMT2ATHRBMAPT | |
| SCHEMBL23398537 | 0.82 | NPC1 (0.51) | NPC1RAB9AKMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |