SCHEMBL23399371

SCHEMBL23399371

Oc1c(-c2ccccc2)cnn1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.62
RAB9A P51151 9/20 0.62
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 2/20 0.50
HSP90AA1 P07900 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
MEN1 O00255 1/20 0.50
ATM Q13315 1/20 0.46
HIF1A Q16665 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
PTGS2 P35354 1/20 0.44
HPGD P15428 2/20 0.43
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401411 0.88 NPC1 (0.68) NPC1RAB9ASMN1; SMN2KMT2AMEN1
SCHEMBL23401483 0.88 NPC1 (0.59) NPC1RAB9ASMN1; SMN2KMT2AHSP90AA1
SCHEMBL23401657 0.84 NPC1 (0.70) NPC1RAB9ASMN1; SMN2KMT2ANFKB1
SCHEMBL23402767 0.84 NPC1 (0.58) NPC1RAB9ASMN1; SMN2KMT2ANFKB1
SCHEMBL23402631 0.81 CA1 (0.47) NPC1RAB9ASMN1; SMN2KMT2AHSP90AA1
SCHEMBL23399941 0.79 CYP17A1 (0.46) NPC1RAB9AKMT2AHIF1ALMNA
SCHEMBL7912407 0.78 NPC1 (0.65) NPC1RAB9ASMN1; SMN2KMT2AHSP90AA1
SCHEMBL23399647 0.78 RAB9A (0.55) NPC1RAB9ASMN1; SMN2KMT2AMEN1
SCHEMBL23399939 0.78 ALDH1A1 (0.47) NPC1RAB9ASMN1; SMN2KMT2AHSP90AA1
SCHEMBL8766069 0.78 NPC1 (0.54) NPC1RAB9ASMN1; SMN2KMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed