SCHEMBL23401700

SCHEMBL23401700

CCCn1nc(-c2ccccc2)c(O)c1-c1ccccc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.51
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
CRHBP P24387 3/20 0.48
CRHR2 Q13324 3/20 0.48
MAPT P10636 2/20 0.48
MAPK1 P28482 2/20 0.48
CASP1 P29466 2/20 0.48
CASP7 P55210 2/20 0.48
TSHR P16473 1/20 0.48
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CNR1 P21554 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
TNNI3 P19429 1/20 0.38
TNNT2 P45379 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400992 0.92 MEN1 (0.50) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23402251 0.92 ESR1 (0.49) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23402723 0.89 CA1 (0.48) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL11866677 0.87 MEN1 (0.56) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23399393 0.83 MEN1 (0.50) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23401769 0.83 MEN1 (0.50) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23403475 0.83 ESR1 (0.40) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23399153 0.83 CA1 (0.43) MEN1KMT2AMAPTMAPK1CASP1
SCHEMBL23399175 0.83 FABP4 (0.37) ESR1MEN1KMT2ACRHBPCRHR2
SCHEMBL23400834 0.81 ESR1 (0.48) ESR1MEN1KMT2ACRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed