SCHEMBL23401899

SCHEMBL23401899

CCc1nn(-c2ccccc2C)c(C(C)C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.38
ALDH1A1 P00352 5/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KMT2A Q03164 2/20 0.37
HTT P42858 1/20 0.37
PDE4A P27815 2/20 0.36
PDE4B Q07343 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
ADORA1 P30542 1/20 0.35
TSHR P16473 1/20 0.34
MAPT P10636 3/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
THRB P10828 1/20 0.34
MAPK1 P28482 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401601 0.89 ALDH1A1 (0.36) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23401284 0.87 KDM4E (0.39) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23400030 0.87 ALDH1A1 (0.34) DHODHALDH1A1L3MBTL1MAPTHSP90AA1
SCHEMBL23400614 0.82 KMT2A (0.43) ALDH1A1L3MBTL1KMT2AHTTTSHR
SCHEMBL23403465 0.82 DHODH (0.41) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23401914 0.81 ALDH1A1 (0.48) ALDH1A1L3MBTL1PDE4APDE4BPDE4C
SCHEMBL23400187 0.81 DHODH (0.40) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23401424 0.81 KDM4E (0.39) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23401745 0.80 DHODH (0.38) DHODHALDH1A1L3MBTL1KMT2AHTT
SCHEMBL23402046 0.80 ALDH1A1 (0.37) DHODHALDH1A1L3MBTL1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed