SCHEMBL23402018

SCHEMBL23402018

CCc1c(O)nn(-c2ccc(OC)cc2)c1-c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
HIF1A Q16665 1/20 0.41
HTT P42858 1/20 0.40
PDE4D Q08499 1/20 0.39
RPA1 P27694 1/20 0.39
PDE5A O76074 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 2/20 0.37
CCNA2 P20248 1/20 0.37
CDK2 P24941 1/20 0.37
CCNA1 P78396 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
KCNH2 Q12809 1/20 0.36
GRM1 Q13255 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400372 0.91 CYP1A2 (0.41) HPGDHIF1AHTTPDE4DRPA1
SCHEMBL23403432 0.90 PDE5A (0.40) HPGDHIF1AHTTPDE4DRPA1
SCHEMBL23401112 0.87 LMNA (0.39) HPGDHIF1APDE4DL3MBTL1LMNA
SCHEMBL23399201 0.87 LMNA (0.47) HPGDHIF1AL3MBTL1LMNAMAPT
SCHEMBL23402315 0.87 HIF1A (0.41) HPGDHIF1AHTTPDE4DRPA1
SCHEMBL23401677 0.85 HTT (0.44) HPGDHIF1AHTTRPA1PDE5A
SCHEMBL23403668 0.84 RPA1 (0.47) HPGDHIF1AHTTRPA1L3MBTL1
SCHEMBL23402956 0.83 PDE4D (0.42) HPGDHIF1AHTTPDE4DRPA1
SCHEMBL23402516 0.81 RPA1 (0.47) HPGDHIF1AHTTRPA1PDE5A
SCHEMBL23403375 0.80 NPC1 (0.47) HPGDHIF1AHTTPDE4DRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed