SCHEMBL23402136

SCHEMBL23402136

CCc1nn(C(C)C)c(-c2cccc(C)c2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.40
HEXB P07686 1/20 0.40
SRC P12931 1/20 0.39
TP53 P04637 4/20 0.37
KCNT1 Q5JUK3 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
NPC1 O15118 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
FYN P06241 2/20 0.34
LMNA P02545 1/20 0.34
HTR2C P28335 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403043 0.90 TP53 (0.41) HEXAHEXBSRCTP53KCNT1
SCHEMBL23400346 0.88 SRC (0.39) HEXAHEXBSRCTP53TRPM8
SCHEMBL23403000 0.87 TP53 (0.42) SRCTP53TRPM8NPC1L3MBTL1
SCHEMBL23400795 0.84 HTR2A (0.43) HEXAHEXBL3MBTL1ALDH1A1POLB
SCHEMBL23402026 0.83 SRC (0.42) SRCNPC1L3MBTL1KMT2AALDH1A1
SCHEMBL23401092 0.83 HTR2A (0.44) HEXAHEXBNPC1KMT2AALDH1A1
SCHEMBL23400213 0.83 HEXA (0.39) HEXAHEXBTP53KCNT1TRPM8
SCHEMBL23403577 0.82 NPC1 (0.45) HEXAHEXBTP53TRPM8NPC1
SCHEMBL23401944 0.82 HEXA (0.43) HEXAHEXBTP53KCNT1TRPM8
SCHEMBL23401984 0.81 SRC (0.39) HEXAHEXBSRCTP53KCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed