SCHEMBL23403000

SCHEMBL23403000

CCCCc1nn(C(C)C)c(-c2cccc(C)c2)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.42
ADORA3 P0DMS8 2/20 0.37
ADORA2A P29274 1/20 0.37
SRC P12931 1/20 0.37
TLR8 Q9NR97 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
GCGR P47871 1/20 0.34
NPC1 O15118 2/20 0.33
KMT2A Q03164 2/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
FYN P06241 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
POLB P06746 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403043 0.93 TP53 (0.41) TP53SRCTLR8MAPTTHRB
SCHEMBL23402136 0.87 HEXA (0.40) TP53SRCMAPTTHRBNPC1
SCHEMBL23402207 0.86 HTR2A (0.39) ADORA3ADORA2AGCGRPOLBSMN1; SMN2
SCHEMBL23399601 0.85 HTR2A (0.40) TP53ADORA3ADORA2ATLR8KDM4E
SCHEMBL23401949 0.84 TP53 (0.41) TP53ADORA3ADORA2ATLR8KDM4E
SCHEMBL23398647 0.84 TP53 (0.40) TP53ADORA3ADORA2ASRCTLR8
SCHEMBL23400346 0.84 SRC (0.39) TP53SRCKDM4EMAPTNPC1
SCHEMBL23403165 0.84 TP53 (0.44) TP53ADORA3ADORA2ATLR8KDM4E
SCHEMBL23400399 0.84 TP53 (0.47) TP53ADORA3ADORA2ATLR8KDM4E
SCHEMBL23399250 0.84 TP53 (0.47) TP53ADORA3ADORA2ATLR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed