SCHEMBL23403138

SCHEMBL23403138

CCCn1[nH]c(-c2ccccc2)c(CC)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYBB P04839 1/20 0.45
NOX4 Q9NPH5 1/20 0.45
NOX1 Q9Y5S8 1/20 0.45
ADORA2B P29275 5/20 0.42
ADORA2A P29274 4/20 0.42
ADORA3 P0DMS8 3/20 0.42
ADORA1 P30542 3/20 0.42
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 5/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP2C9 P11712 2/20 0.39
HPGD P15428 1/20 0.39
KDM5B Q9UGL1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403309 0.91 MEN1 (0.57) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23400114 0.89 CYBB (0.56) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23399643 0.87 CYBB (0.44) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23401157 0.87 CYBB (0.48) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23403275 0.86 ADORA2A (0.43) CYBBNOX4NOX1ADORA2BADORA2A
SCHEMBL23401142 0.85 CYBB (0.41) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23402634 0.84 KMT2A (0.38) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL23399420 0.83 MEN1 (0.43) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23401629 0.83 KDM4E (0.44) MEN1KMT2ACYBBNOX4NOX1
SCHEMBL23399055 0.82 ALDH1A1 (0.53) MEN1KMT2ACYBBNOX4NOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed