SCHEMBL23403285

SCHEMBL23403285

CCCCn1nc(O)cc1C

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
TYR P14679 1/20 0.41
ESR1 P03372 2/20 0.40
GLS O94925 1/20 0.40
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
NR1H3 Q13133 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.35
SLC9A1 P19634 1/20 0.35
MPO P05164 2/20 0.35
HCAR3 P49019 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
LMNA P02545 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400742 0.88 ADORA2A (0.44) KDM4ETYRESR1GLSALDH1A1
SCHEMBL6114764 0.80 GLS (0.62) KDM4EGLSALDH1A1NR1H3GAA
SCHEMBL23399117 0.79
SCHEMBL23401425 0.79 ESR1 (0.39) KDM4ETYRESR1ALDH1A1KMT2A
SCHEMBL23403019 0.78 ESR1 (0.38) KDM4ETYRESR1NR1H3SLC9A1
SCHEMBL23403308 0.78 ESR1 (0.38) KDM4ETYRESR1NR1H3SLC9A1
SCHEMBL31052600 0.77 KDM4E (0.41) KDM4ETYRESR1GLSALDH1A1
SCHEMBL10284721 0.77 GLS (0.44) KDM4EGLSALDH1A1KMT2ANR1H3
SCHEMBL23398463 0.77 CNR1 (0.48) ESR1ALDH1A1KMT2ANR1H3MEN1
SCHEMBL23403574 0.77 CNR1 (0.53) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed