SCHEMBL23403287

SCHEMBL23403287

Cc1cccc(-c2[nH]n(-c3ccccc3C)c(=O)c2C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH3 Q96Q83 2/20 0.47
NOX4 Q9NPH5 4/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 3/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MEN1 O00255 2/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
MPL P40238 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400441 0.87 ALKBH3 (0.37) ALKBH3NOX4MAPTLMNAHTT
SCHEMBL23400710 0.87 ALKBH3 (0.49) ALKBH3NOX4MAPTLMNAKMT2A
SCHEMBL23399948 0.86 ALKBH3 (0.50) ALKBH3MAPTLMNAHTTKMT2A
SCHEMBL23399735 0.84 NOX4 (0.39) ALKBH3NOX4MAPTLMNAHTT
SCHEMBL23401701 0.84 ALKBH3 (0.48) ALKBH3MAPTLMNAHTTKMT2A
SCHEMBL23402976 0.84 ALKBH3 (0.47) ALKBH3NOX4MAPTLMNAHTT
SCHEMBL23398547 0.83 ALKBH3 (0.52) ALKBH3MAPTLMNAHTTKMT2A
SCHEMBL23398889 0.82 NOX4 (0.50) ALKBH3NOX4MAPTLMNAHTT
SCHEMBL23398831 0.81 ALKBH3 (0.47) ALKBH3NOX4MAPTLMNAHTT
SCHEMBL23398881 0.80 ALKBH3 (0.49) ALKBH3MAPTLMNAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed