Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | UGCG | Q16739 | 2/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535824 | 1.00 | TSHR (0.61) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL16595002 | 0.98 | TSHR (0.64) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL21184508 | 0.98 | TSHR (0.64) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL25195898 | 0.98 | TSHR (0.64) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL16594712 | 0.95 | TSHR (0.61) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011715 | 0.95 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011734 | 0.95 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011595 | 0.95 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011624 | 0.95 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011646 | 0.95 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573507-B | Small molecules | 邓迪大学 | 2023-11-14 | — | — | CN | disclosed |
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-11261179-B2 | Small molecules | UNIVERSITY OF DUNDEE (GB) | 2022-03-01 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| CN-110573507-A | small molecules | 邓迪大学 | 2019-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127257-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | TSHR 3941/4885L3MBTL1 529/4885TDP1 3786/4885 |
| US-11261179-B2 | Small molecules | ADRM1, MDM2, UBE2B | TSHR 3941/4885L3MBTL1 529/4885TDP1 3786/4885 |
| US-20210163469-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | TSHR 3941/4885L3MBTL1 529/4885TDP1 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.