Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 3/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | CYCS | P99999 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Exeporfinium SCHEMBL585997 | 0.83 | STAT3 (0.52) | STAT3STAT1CHRNB4CHRNA3CHRNA7 | |
| Exeporfinium SCHEMBL5012396 | 0.82 | STAT3 (0.51) | STAT3STAT1CHRNB4CHRNA3CHRNA7 | |
| Exeporfinium SCHEMBL584418 | 0.82 | STAT3 (0.51) | STAT3STAT1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL12633142 | 0.82 | STAT3 (0.55) | STAT3STAT1TOP1TERTABCG2 | |
| SCHEMBL584793 | 0.81 | STAT3 (0.52) | STAT3STAT1TERTHDAC6 | |
| Hydrochloric Acid SCHEMBL29648896 | 0.81 | STAT3 (0.48) | STAT3STAT1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL21523873 | 0.80 | STAT3 (0.53) | STAT3STAT1TERT | |
| Hydrochloric Acid SCHEMBL584374 | 0.80 | STAT3 (0.51) | STAT3STAT1TERTHDAC6 | |
| Hydrochloric Acid SCHEMBL29883333 | 0.80 | STAT3 (0.51) | STAT3STAT1TERTHDAC6 | |
| SCHEMBL585086 | 0.80 | STAT3 (0.55) | STAT3STAT1TOP1TERTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | claimed |
| EP-1558616-B1 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2008-02-27 | — | — | EP | claimed |