Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29996029 | 1.00 | SNCA (0.68) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL10057827 | 0.87 | SNCA (0.77) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL23407836 | 0.86 | SNCA (0.69) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL23407806 | 0.85 | SNCA (0.61) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL30203697 | 0.85 | SNCA (0.61) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL23407797 | 0.85 | SNCA (0.61) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL29995270 | 0.85 | SNCA (0.61) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL30203563 | 0.84 | SNCA (0.49) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL23407770 | 0.84 | SNCA (0.49) | SNCASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL22890886 | 0.83 | SNCA (0.73) | SNCASMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099518-A1 | NOVEL COMPOUNDS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH THE AGGREGATION OF ALPHA-SYNUCLEIN | MODAG GMBH (DE) | 2021-05-27 | — | — | WO | disclosed |