Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.53 |
| ▸ | GRM5 | P41594 | 10/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290520 | 0.88 | GRM1 (0.53) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL29150020 | 0.88 | GRM1 (0.53) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL31704677 | 0.84 | GRM1 (0.50) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL31705698 | 0.84 | GRM1 (0.50) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL30711189 | 0.82 | RAB9A (0.44) | GRM1GRM5KDM4E | |
| SCHEMBL9094797 | 0.80 | PDK4 (0.49) | GRM1GRM5GPR119PDK4 | |
| SCHEMBL30308912 | 0.80 | GRM1 (0.64) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL3642040 | 0.80 | GRM1 (0.54) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL16544582 | 0.79 | GRM5 (0.59) | GRM1GRM5PDK4NAMPTWNT3A | |
| SCHEMBL25480230 | 0.79 | GRM1 (0.59) | GRM1GRM5GPR119PDK4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102468-A1 | SUBSTITUTED 1,5-NAPHTHYRIDINES OR QUINOLINES AS ALK5 INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2021-05-27 | — | — | WO | disclosed |