Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.32 |
| ▸ | PIM1 | P11309 | 3/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408679 | 0.90 | NTRK1 (0.35) | NTRK1ENPP2HPGDSNTRK3NTRK2 | |
| SCHEMBL23408738 | 0.85 | NTRK1 (0.35) | NTRK1ENPP2HPGDSPIM1AAK1 | |
| SCHEMBL23408654 | 0.80 | NTRK1 (0.49) | NTRK1 | |
| SCHEMBL23408817 | 0.76 | IRAK4 (0.36) | NTRK1PIM1AAK1CCNT1CDK9 | |
| SCHEMBL23408585 | 0.76 | IRAK4 (0.36) | NTRK1PIM1AAK1CCNT1CDK9 | |
| SCHEMBL23408757 | 0.74 | KDM4E (0.36) | NTRK1PIM1 | |
| SCHEMBL23408626 | 0.72 | IRAK4 (0.38) | NTRK1NTRK3NTRK2PIM1AAK1 | |
| SCHEMBL23408752 | 0.72 | DYRK1A (0.35) | PIM1AAK1CCNT1CDK9 | |
| SCHEMBL23408584 | 0.72 | DYRK1A (0.35) | PIM1AAK1CCNT1CDK9 | |
| SCHEMBL23408809 | 0.71 | PIM1 (0.33) | PIM1AAK1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098745-A1 | PREPARATION AND APPLICATION OF A CLASS OF PROTEIN RECEPTOR KINASE INHIBITORS | 上海轶诺药业有限公司 | 2021-05-27 | — | — | WO | disclosed |