Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16966572 | 0.84 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL29981543 | 0.84 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL344654 | 0.84 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL4863253 | 0.83 | KDM4E (0.50) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL28210923 | 0.83 | MAPK1 (0.68) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL9772059 | 0.83 | KDM4E (0.68) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL4865098 | 0.82 | MAPK1 (0.49) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| Phthalic Acid SCHEMBL27855768 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL11963919 | 0.81 | HSD17B10 (0.50) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL16681319 | 0.80 | ELANE (0.36) | KDM4EHSD17B10HPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1563820-B1 | DENTAL ADHESIVE COMPOSITION | SUN MEDICAL CO LTD (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-7504443-B2 | Dental adhesive composition | SUN MEDICAL CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20050256221-A1 | Dental adhesive composition | SUN MEDICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1563820-A1 | DENTAL ADHESIVE COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2005-08-17 | — | — | EP | disclosed |