Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 16/20 | 0.62 |
| ▸ | TTBK2 | Q6IQ55 | 16/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26784714 | 0.87 | EGFR (0.68) | TTBK1TTBK2EGFRAURKAAURKB | |
| SCHEMBL24457923 | 0.85 | TTBK1 (0.58) | TTBK1TTBK2EGFRAURKAAURKB | |
| SCHEMBL16363320 | 0.83 | TTBK1 (0.84) | TTBK1TTBK2 | |
| SCHEMBL7026408 | 0.81 | TTBK1 (0.71) | TTBK1TTBK2EGFRAURKAAURKB | |
| Hydrochloric Acid SCHEMBL7019896 | 0.80 | TTBK1 (0.69) | TTBK1TTBK2EGFRAURKAAURKB | |
| SCHEMBL7021509 | 0.78 | EGFR (0.70) | TTBK1TTBK2EGFRAURKAAURKB | |
| Hydrochloric Acid SCHEMBL7020471 | 0.77 | EGFR (0.69) | TTBK1TTBK2EGFRAURKAAURKB | |
| SCHEMBL14845851 | 0.77 | TNNI3K (0.55) | TNNI3K | |
| SCHEMBL168084 | 0.76 | TTBK1 (1.00) | TTBK1TTBK2EGFRAURKAAURKB | |
| SCHEMBL24882299 | 0.76 | TTBK1 (1.00) | TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| WO-2022106902-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2022-05-27 | — | — | WO | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | TTBK1 3603/4885TTBK2 2919/4885EGFR 308/4885 |
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | ABCG2, ABCB1, ARSA | TTBK1 2180/4885TTBK2 1541/4885EGFR 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.