Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.68 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.68 |
| ▸ | RET | P07949 | 1/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.68 |
| ▸ | MARK3 | P27448 | 1/20 | 0.68 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.68 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.68 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.68 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.68 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.68 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.68 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.68 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.68 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.68 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.68 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.68 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.68 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.68 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.68 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991803 | 0.96 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL25649692 | 0.90 | FGFR1 (0.67) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL21430743 | 0.90 | FGFR1 (0.67) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL23409092 | 0.88 | FGFR2 (0.60) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63550 | 0.88 | FGFR1 (0.65) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL25068999 | 0.88 | FGFR1 (0.65) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63045 | 0.87 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63044 | 0.87 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64674 | 0.86 | FGFR1 (0.63) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63114 | 0.86 | FGFR2 (0.62) | FGFR1NTRK1RETPDGFRBMARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |