Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.65 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.65 |
| ▸ | MARK3 | P27448 | 1/20 | 0.65 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.65 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.65 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.65 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.65 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.65 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.65 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.65 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.65 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.65 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.65 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.65 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.65 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.65 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.65 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25068960 | 0.89 | FGFR2 (0.58) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL23409091 | 0.88 | FGFR1 (0.68) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL25649692 | 0.87 | FGFR1 (0.67) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL21430743 | 0.87 | FGFR1 (0.67) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63571 | 0.87 | FGFR1 (0.62) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63550 | 0.85 | FGFR1 (0.65) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63045 | 0.84 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63044 | 0.84 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL22991803 | 0.84 | FGFR1 (0.64) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64674 | 0.84 | FGFR1 (0.63) | FGFR1NTRK1RETPDGFRBMARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | FGFR1 109/4885NTRK1 2721/4885RET 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.