Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 7/20 | 1.00 |
| ▸ | CDK2 | P24941 | 7/20 | 1.00 |
| ▸ | CCNK | O75909 | 7/20 | 1.00 |
| ▸ | CCND3 | P30281 | 7/20 | 1.00 |
| ▸ | CDK9 | P50750 | 7/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 7/20 | 1.00 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.78 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.71 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | AXL | P30530 | 1/20 | 0.70 |
| ▸ | NEK2 | P51955 | 1/20 | 0.70 |
| ▸ | BRD4 | O60885 | 2/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394835 | 1.00 | CCNA2 (1.00) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL30395236 | 0.90 | CCNA2 (1.00) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL30394638 | 0.89 | CCNA2 (1.00) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL30395234 | 0.89 | CCNA2 (1.00) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL18696335 | 0.88 | CCNK (0.79) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL30394643 | 0.88 | CCND3 (1.00) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL25068880 | 0.87 | CCNK (0.79) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL25032397 | 0.86 | CCNA2 (0.75) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL32690385 | 0.85 | EGFR (0.76) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL25668162 | 0.84 | EGFR (0.81) | CCNA2CDK2CCNKCCND3CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | CCNA2 4846/4885CDK2 3582/4885CCNK 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.