Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CCND2 | P30279 | 1/20 | 0.53 |
| ▸ | CCND3 | P30281 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.45 |
| ▸ | ITK | Q08881 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | TEC | P42680 | 1/20 | 0.45 |
| ▸ | TXK | P42681 | 1/20 | 0.45 |
| ▸ | BMX | P51813 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533535 | 0.77 | BRAF (0.54) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL19544927 | 0.76 | SYK (0.57) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL29575809 | 0.76 | BRAF (0.65) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL31688432 | 0.76 | BRAF (0.52) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL15987166 | 0.76 | BRAF (0.55) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL17409829 | 0.76 | BRAF (0.55) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL22909438 | 0.75 | SYK (0.56) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL29729055 | 0.75 | SYK (0.56) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL19544928 | 0.75 | MAPT (0.52) | BRAFCDK4CCND1CCND2CCND3 | |
| SCHEMBL19754300 | 0.74 | MAPT (0.54) | BRAFCDK4CCND1CCND2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |