Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409072 | 0.90 | TSHR (0.53) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL25068885 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL23409102 | 0.84 | ALDH1A1 (0.70) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL13770253 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL3875081 | 0.82 | KMT2A (0.56) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL21511688 | 0.81 | KMT2A (0.49) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL18215407 | 0.81 | GLA (0.61) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL18215303 | 0.81 | GLA (0.61) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL18215370 | 0.81 | GLA (0.61) | ALDH1A1KDM4ETSHRPOLBDRD2 | |
| SCHEMBL25069181 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRPOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |