SCHEMBL23409199

SCHEMBL23409199

CC(C)(C)OC(=O)Nc1cc(NC(=O)c2ccccc2C(=O)O)ccc1N

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.54
ALDH1A1 P00352 3/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
CYP1A2 P05177 1/20 0.51
GFER P55789 2/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
PPARG P37231 4/20 0.43
PPARA Q07869 4/20 0.43
NR1H4 Q96RI1 4/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19799377 0.86 RXFP1 (0.54) RXFP1ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL6816151 0.84 ALDH1A1 (0.63) RXFP1ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL23409250 0.82 CYP1A2 (0.50) RXFP1ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL19799379 0.81 RXFP1 (0.48) RXFP1ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL23409194 0.80 RXFP1 (0.47) RXFP1ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL7076492 0.77 PTGS1 (0.59) RXFP1ALDH1A1KMT2AMEN1
SCHEMBL18132595 0.77 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1CYP1A2GFER
SCHEMBL3790650 0.76 HDAC2 (0.65)
SCHEMBL7570500 0.76 GAA (0.60) ALDH1A1KMT2AMEN1CYP1A2GFER
SCHEMBL14876843 0.76 AAK1 (0.46) ALDH1A1KMT2AMEN1GFERL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384204-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2022-07-12 US disclosed
US-20210155755-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2021-05-27 US disclosed