Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.68 |
| ▸ | DRD2 | P14416 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | HRH1 | P35367 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728636 | 0.86 | HTR6 (0.74) | HTR6KCNH2DRD2HTR2AHTR1A | |
| SCHEMBL23409210 | 0.86 | HTR6 (0.74) | HTR6KCNH2DRD2HTR2AHTR1A | |
| SCHEMBL30083635 | 0.86 | HTR6 (0.78) | HTR6KCNH2DRD2HTR2AHTR1A | |
| SCHEMBL23409241 | 0.86 | HTR6 (0.78) | HTR6KCNH2DRD2HTR2AHTR1A | |
| SCHEMBL23409240 | 0.85 | HTR6 (0.79) | HTR6KCNH2DRD2HTR2AHTR1A | |
| Bromide SCHEMBL30647908 | 0.85 | HTR6 (0.77) | HTR6KCNH2DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL30083608 | 0.85 | HTR6 (0.77) | HTR6KCNH2DRD2HTR2AHTR1A | |
| SCHEMBL30728645 | 0.85 | HTR6 (0.79) | HTR6KCNH2DRD2HTR2AHTR1A | |
| Sulfuric Acid SCHEMBL30083657 | 0.85 | HTR6 (0.74) | HTR6KCNH2DRD2HTR2AHTR1A | |
| Cadaverine Tartrate SCHEMBL30083652 | 0.84 | HTR6 (0.73) | HTR6KCNH2DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098737-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 上海枢境生物科技有限公司 | 2021-05-27 | — | — | WO | disclosed |