Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409977 | 0.92 | KRAS (0.52) | KRAS | |
| SCHEMBL29903156 | 0.91 | KRAS (0.46) | KRAS | |
| SCHEMBL23413429 | 0.91 | KRAS (0.46) | KRAS | |
| SCHEMBL23409327 | 0.87 | KRAS (0.48) | KRAS | |
| SCHEMBL29344388 | 0.86 | KRAS (0.50) | KRAS | |
| SCHEMBL23409336 | 0.83 | KRAS (0.68) | KRAS | |
| SCHEMBL29903158 | 0.83 | KRAS (0.50) | KRAS | |
| SCHEMBL23413758 | 0.83 | KRAS (0.50) | KRAS | |
| SCHEMBL30998647 | 0.83 | KRAS (0.42) | KRAS | |
| SCHEMBL25336815 | 0.82 | KRAS (0.40) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106231-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-03 | — | — | WO | disclosed |