Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409214 | 0.96 | POLB (0.60) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409610 | 0.87 | POLB (0.57) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409958 | 0.84 | KMT2A (0.48) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409215 | 0.82 | POLB (0.54) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409221 | 0.81 | POLB (0.42) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409966 | 0.80 | POLB (0.46) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL7138423 | 0.79 | CYP11B1 (0.66) | KMT2ATDP1CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL23409561 | 0.78 | HRH3 (0.46) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL23409730 | 0.77 | POLB (0.41) | POLBKMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL1762275 | 0.77 | POLB (0.57) | POLBKMT2ATDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098737-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 上海枢境生物科技有限公司 | 2021-05-27 | — | — | WO | disclosed |