Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409730 | 0.96 | POLB (0.41) | POLBCYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409630 | 0.89 | CYP11B1 (0.35) | POLBCYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409552 | 0.81 | POLB (0.61) | POLBCYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409641 | 0.78 | OPRM1 (0.37) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409214 | 0.77 | POLB (0.60) | POLBCYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409643 | 0.74 | CYP11B1 (0.40) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL30728646 | 0.73 | DRD2 (0.59) | HTR2A | |
| SCHEMBL30728640 | 0.73 | DRD2 (0.58) | HTR2A | |
| SCHEMBL30728644 | 0.72 | DRD2 (0.63) | HTR2A | |
| SCHEMBL23409644 | 0.71 | MAPT (0.39) | CYP11B1CYP11B2KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098737-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 上海枢境生物科技有限公司 | 2021-05-27 | — | — | WO | disclosed |