⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182009 | 0.79 | — | — | |
| SCHEMBL262994 | 0.78 | PYGM (0.35) | — | |
| SCHEMBL3622646 | 0.78 | — | — | |
| SCHEMBL7141745 | 0.78 | — | — | |
| SCHEMBL11029531 | 0.77 | HDAC2 (0.31) | — | |
| SCHEMBL936174 | 0.76 | — | — | |
| SCHEMBL7411108 | 0.76 | — | — | |
| SCHEMBL3328286 | 0.76 | — | — | |
| SCHEMBL15363888 | 0.74 | — | — | |
| SCHEMBL12609413 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414308-A1 | RADIOLABELLING METHODS | Hammersmith Imanet, Ltd (GB) | 2012-02-08 | — | — | EP | disclosed |
| US-20120004404-A1 | RADIOLABELLING METHODS | HAMMERSMITH IMANET LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| WO-2010117557-A1 | RADIOLABELLING METHODS | HAMMERSMITH IMANET LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |
| US-7041851-B2 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1175388-B1 | SPECT IMAGING AGENTS FOR SEROTONIN TRANSPORTERS | UNIV PENNSYLVANIA (US) | 2006-03-15 | — | — | EP | disclosed |
| US-6921840-B1 | SPECT imaging agents for serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-07-26 | — | — | US | disclosed |
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-12-25 | — | — | US | disclosed |
| WO-2003078393-A2 | FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-09-25 | — | — | WO | disclosed |
| EP-1175388-A4 | SPECT IMAGING AGENTS FOR SEROTONIN TRANSPORTERS | UNIV PENNSYLVANIA (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-1175388-A1 | SPECT IMAGING AGENTS FOR SEROTONIN TRANSPORTERS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066537-A1 | SPECT IMAGING AGENTS FOR SEROTONIN TRANSPORTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |
| US-5216028-A | Therapeutic uses of a diphenylsulfide compound to treat depression and effect serotonin uptake | BURROUGHS WELLCOME CO. (US) | 1993-06-01 | — | — | US | disclosed |
| US-5104897-A | Administering anxiolytic agents | BURROUGHS WELLCOME CO. (US) | 1992-04-14 | — | — | US | disclosed |
| US-5095039-A | Antidepressants | BURROUGHS WELLCOME CO. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0402097-A1 | Halogen substituted diphenylsulfides | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-12 | — | — | EP | disclosed |