Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 16/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | NCK1 | P16333 | 1/20 | 0.41 |
| ▸ | CYBB | P04839 | 2/20 | 0.40 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412664 | 0.90 | NCF1 (0.54) | NCF1BACE1CYBBNOX5 | |
| SCHEMBL23412248 | 0.90 | NCF1 (0.54) | NCF1BACE1CYBBNOX5 | |
| SCHEMBL23412180 | 0.90 | NCF1 (0.54) | NCF1BACE1CYBBNOX5 | |
| SCHEMBL23412149 | 0.71 | NCF1 (1.00) | NCF1CYBBNOX5 | |
| SCHEMBL23412826 | 0.71 | NCF1 (1.00) | NCF1CYBBNOX5 | |
| SCHEMBL23412091 | 0.71 | NCF1 (1.00) | NCF1CYBBNOX5 | |
| SCHEMBL23412138 | 0.71 | NCF1 (1.00) | NCF1CYBBNOX5 | |
| SCHEMBL23412694 | 0.70 | NCF1 (0.56) | NCF1BACE1CYBBNOX5 | |
| SCHEMBL31091801 | 0.70 | BACE1 (0.58) | NCF1PLAUBACE1NCK1 | |
| SCHEMBL681625 | 0.70 | BACE1 (0.58) | NCF1PLAUBACE1NCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | claimed |