Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 13/20 | 0.67 |
| ▸ | NOS1 | P29475 | 3/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23412340 | 0.96 | NCF1 (0.74) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23412733 | 0.96 | NCF1 (0.74) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23412990 | 0.96 | NCF1 (0.74) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23412873 | 0.96 | NCF1 (0.74) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23412998 | 0.96 | NCF1 (0.74) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23413120 | 0.92 | NCF1 (0.70) | NCF1NOS1NOS3MIF | |
| Trifluoroacetic Acid SCHEMBL23412294 | 0.87 | NCF1 (0.75) | NCF1MIF | |
| Trifluoroacetic Acid SCHEMBL23412351 | 0.87 | NCF1 (0.75) | NCF1MIF | |
| SCHEMBL23452962 | 0.85 | NCF1 (0.90) | NCF1NOS1NOS2 | |
| SCHEMBL23413036 | 0.81 | NCF1 (1.00) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | disclosed |