Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.69 |
| ▸ | NCF1 | P14598 | 4/20 | 0.68 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884656 | 0.88 | MCHR1 (0.82) | MCHR1NCF1 | |
| SCHEMBL5884109 | 0.86 | MCHR1 (0.85) | MCHR1NCF1 | |
| SCHEMBL5884059 | 0.83 | NCF1 (0.65) | MCHR1NCF1PLAU | |
| SCHEMBL5884456 | 0.82 | MCHR1 (1.00) | MCHR1NCF1 | |
| SCHEMBL5884249 | 0.82 | MCHR1 (0.73) | MCHR1NCF1 | |
| SCHEMBL5884449 | 0.81 | NCF1 (1.00) | MCHR1NCF1 | |
| SCHEMBL23412162 | 0.81 | NCF1 (1.00) | MCHR1NCF1 | |
| SCHEMBL23412964 | 0.81 | NCF1 (1.00) | MCHR1NCF1 | |
| SCHEMBL7261226 | 0.81 | MCHR1 (0.78) | MCHR1NCF1 | |
| SCHEMBL5883752 | 0.81 | MCHR1 (1.00) | MCHR1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | claimed |
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | disclosed |