Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | DPP4 | P27487 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.77 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.77 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.77 |
| ▸ | GAPDH | P04406 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.77 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.77 |
| ▸ | STAT6 | P42226 | 1/20 | 0.77 |
| ▸ | PI4KA | P42356 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.77 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.77 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.77 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.77 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658306 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL546471 | 0.91 | ADORA3 (0.77) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL6142045 | 0.91 | ADORA3 (0.77) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL3369124 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL21418864 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL29748808 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL16359953 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL15755555 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL23547979 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL1066939 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1SMN1; SMN2DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428658-B2 | Methods and compositions for enzymatic polymerization of N3′→P5′ phosphoramidate DNA | THE GENERAL HOSPITAL CORPORATION (US) | 2025-09-30 | — | — | US | claimed |
| US-20240309418-A1 | ENZYMATIC METHODS AND COMPOSITIONS FOR POLYMERIZATION OF PHOSPHORAMIDATE AND THIOPHOSPHORAMIDATE-LINKED DNA | MASSACHUSETTS GEN HOSPITAL (US) | 2024-09-19 | — | — | US | claimed |
| US-20230026693-A1 | Methods and Compositions for Enzymatic Polymerization of N3` -> P5` Phosphoramidate DNA | THE GENERAL HOSPITAL CORPORATION | 2023-01-26 | — | — | US | claimed |
| WO-2021108632-A1 | METHODS AND COMPOSITIONS FOR ENZYMATIC POLYMERIZATION OF N3' -> P5' PHOSPHORAMIDATE DNA | THE GENERAL HOSPITAL CORPORATION (US) | 2021-06-03 | — | — | WO | claimed |
| US-12428658-B2 | Methods and compositions for enzymatic polymerization of N3′→P5′ phosphoramidate DNA | THE GENERAL HOSPITAL CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| US-20240309418-A1 | ENZYMATIC METHODS AND COMPOSITIONS FOR POLYMERIZATION OF PHOSPHORAMIDATE AND THIOPHOSPHORAMIDATE-LINKED DNA | MASSACHUSETTS GEN HOSPITAL (US) | 2024-09-19 | — | — | US | disclosed |
| US-20230026693-A1 | Methods and Compositions for Enzymatic Polymerization of N3` -> P5` Phosphoramidate DNA | THE GENERAL HOSPITAL CORPORATION | 2023-01-26 | — | — | US | disclosed |