Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26428772 | 0.91 | TLR4 (0.58) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL24668231 | 0.90 | TLR4 (0.45) | TLR4HPGDRECQLALDH1A1MEN1 | |
| SCHEMBL871525 | 0.85 | TLR4 (0.71) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL871966 | 0.85 | TLR4 (0.71) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL872429 | 0.85 | TLR4 (0.60) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL871427 | 0.85 | TLR4 (0.62) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL871862 | 0.82 | TLR4 (0.56) | TLR4HPGDRECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL26422913 | 0.81 | TLR4 (0.45) | TLR4HPGDRECQLALDH1A1RAB9A | |
| SCHEMBL871345 | 0.80 | TLR4 (0.71) | TLR4HPGDRECQLCA1CA2 | |
| SCHEMBL26446125 | 0.80 | TLR4 (0.44) | TLR4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |