Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23417844 | 0.90 | TLR4 (0.56) | TLR4ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL23417853 | 0.87 | TLR4 (0.51) | TLR4 | |
| SCHEMBL26428772 | 0.83 | TLR4 (0.58) | TLR4ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL23417983 | 0.82 | TLR4 (0.41) | TLR4 | |
| SCHEMBL26446125 | 0.80 | TLR4 (0.44) | TLR4ALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL26422913 | 0.79 | TLR4 (0.45) | TLR4ALDH1A1HPGDRECQL | |
| SCHEMBL23417821 | 0.78 | TLR4 (0.52) | TLR4CYP3A4 | |
| SCHEMBL29344080 | 0.78 | TLR4 (0.42) | TLR4ALDH1A1HPGD | |
| SCHEMBL23417719 | 0.77 | TLR4 (0.62) | TLR4CYP3A4 | |
| SCHEMBL23417790 | 0.75 | TLR4 (0.49) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |