Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 6/20 | 0.58 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17359308 | 0.81 | KDM4A (0.67) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL13645407 | 0.80 | KDM4A (0.84) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL14984138 | 0.80 | KDM4A (0.79) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL12533259 | 0.79 | KDM4A (0.88) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL14984144 | 0.77 | KDM4A (0.73) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL10103995 | 0.76 | KDM4A (0.88) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL13043665 | 0.75 | KDM4A (0.61) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL13924724 | 0.75 | KDM4A (0.97) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL10844383 | 0.74 | KDM4A (1.00) | KDM4AKDM2AMAPTKMT2AGAA | |
| SCHEMBL13417473 | 0.74 | KDM4A (1.00) | KDM4AKDM2AMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021450-B2 | PSMA targeted fluorescent agents for image guided surgery | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021450-B2 | PSMA targeted fluorescent agents for image guided surgery | KLK3, FOLH1, SPR | KDM4A 2410/4885KDM2A 2226/4885MAPT 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.