SCHEMBL2343243

SCHEMBL2343243

CCCCCC1CCCC[C]1C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 0.40
NOS2 P35228 5/20 0.40
CYP1A2 P05177 4/20 0.39
EPHX1 P07099 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
NOS3 P29474 3/20 0.34
ALDH1A1 P00352 1/20 0.33
S1PR2 O95136 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
S1PR5 Q9H228 1/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039824 0.94 CYP1A2 (0.45) NOS1NOS2CYP1A2NOS3ALDH1A1
SCHEMBL9318409 0.88 CYP1A2 (0.41) NOS1NOS2CYP1A2NOS3
SCHEMBL486918 0.85 NOS1 (0.41) NOS1NOS2CYP1A2NOS3ALDH1A1
SCHEMBL486904 0.83 NOS1 (0.43) NOS1NOS2CYP1A2NOS3ALDH1A1
SCHEMBL487110 0.79
SCHEMBL536549 0.78 NPC1 (0.48) NOS1NOS2CYP1A2ALDH1A1
SCHEMBL11872784 0.78 NOS1 (0.39) NOS1NOS2CYP1A2EPHX1CHRNB2
SCHEMBL25190402 0.77 NPC1 (0.47) NOS1NOS2CYP1A2ALDH1A1
SCHEMBL4441775 0.77 NPC1 (0.47) NOS1NOS2CYP1A2ALDH1A1
SCHEMBL9158941 0.77 NPC1 (0.47) NOS1NOS2CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279874-B Grease composition 出光兴产株式会社 2024-02-13 CN claimed
CN-115279875-B Grease composition 出光兴产株式会社 2024-01-12 CN claimed
CN-113490733-B Grease composition, and method and device for lubricating sliding mechanism using same 出光兴产株式会社 2023-07-28 CN claimed
CN-105008503-B Grease composition for bearing 出光兴产株式会社 2019-04-12 CN claimed
US-5512188-A DURABLE LUBRICANTS HAVING REDUCED FLAKING NIPPON OIL CO., LTD. (JP) 1996-04-30 US claimed
US-5462683-A Thickener, boron nitride powder, extreme pressure agent comprising molybdenum compound, and sulfur and phosphorus containing compounds; nonflaking NIPPON OIL CO., LTD. (JP) 1995-10-31 US claimed
US-5059336-A Comprising synthetic lubricant base oil, urea thickener, sorbitan monooleate, an organobarium sulfonate and barium lanolate; corrosion resistance; durability NIPPON SEIKO KABUSHIKI KAISHA (JP) 1991-10-22 US claimed
US-5043085-A Wear resistant lubricant NIPPON MITSUBSHI OIL CORPORATION (JP) 1991-08-27 US claimed
EP-0274756-B1 UREA-URETHANE GREASE COMPOSITION NIPPON OIL CO., LTD. (JP) 1990-10-31 EP claimed
US-4915860-A THICNENERS; NONHARDENING; SHEAR RESISTANCE; EXTREME TEMPERATURE LUBRICANTS NIPPON OIL CO., LTD. (JP) 1990-04-10 US claimed
US-4780231-A LUBRICANT BASE OIL AND DIUREA THICKENER NIPPON OIL CO., LTD. (JP) 1988-10-25 US claimed
EP-0274756-A2 Urea-urethane grease composition NIPPON OIL CO., LTD. (JP) 1988-07-20 EP claimed
US-4115284-A POLYOXYETHYLENE GLYCOL MONOETHER, GELLING AGENT NIPPON OIL CO., LTD. (JP) 1978-09-19 US claimed
CN-117580934-A Grease composition 出光兴产株式会社 2024-02-20 CN disclosed
CN-115279874-B Grease composition 出光兴产株式会社 2024-02-13 CN disclosed
CN-115279875-B Grease composition 出光兴产株式会社 2024-01-12 CN disclosed
US-4915860-A THICNENERS; NONHARDENING; SHEAR RESISTANCE; EXTREME TEMPERATURE LUBRICANTS NIPPON OIL CO., LTD. (JP) 1990-04-10 US disclosed
US-4780231-A LUBRICANT BASE OIL AND DIUREA THICKENER NIPPON OIL CO., LTD. (JP) 1988-10-25 US disclosed
EP-0274756-A2 Urea-urethane grease composition NIPPON OIL CO., LTD. (JP) 1988-07-20 EP disclosed
US-4115284-A POLYOXYETHYLENE GLYCOL MONOETHER, GELLING AGENT NIPPON OIL CO., LTD. (JP) 1978-09-19 US disclosed