Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | APEX1 | P27695 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | MMP1 | P03956 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 3/20 | 0.58 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440445 | 0.89 | POLH (0.68) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23442318 | 0.86 | POLH (0.70) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440441 | 0.85 | POLH (0.71) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440452 | 0.84 | POLH (0.67) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23442026 | 0.84 | EPHX2 (0.65) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440444 | 0.83 | POLH (0.69) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440442 | 0.82 | POLH (0.67) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23441997 | 0.82 | POLH (0.67) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440421 | 0.82 | POLH (0.70) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL7202826 | 0.81 | POLH (1.00) | POLHKDM4EPOLBRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104416-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (CN) | 2021-06-03 | — | — | WO | disclosed |