Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.71 |
| ▸ | POLH | Q9Y253 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440417 | 0.89 | EPHX2 (0.70) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL27914721 | 0.85 | EPHX2 (0.80) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23442024 | 0.84 | EPHX2 (0.77) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL6072546 | 0.83 | EPHX2 (1.00) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23442126 | 0.83 | EPHX2 (0.88) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23442030 | 0.83 | EPHX2 (0.88) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23441996 | 0.82 | EPHX2 (0.82) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23440413 | 0.82 | EPHX2 (0.71) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL23440447 | 0.81 | POLH (0.69) | EPHX2POLHMEN1KMT2AKDM4E | |
| SCHEMBL4175201 | 0.81 | POLH (0.76) | EPHX2POLHMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104416-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (CN) | 2021-06-03 | — | — | WO | disclosed |